This is our first trip and we're using Disney's Magical Express to get from the Orlando Airport to the resort. I don't really know what to expect. I realize I don't need to pick up my bags, but what else do I need to need to know? It all seems so weird - but very nice too in not having to worry about getting a rental car, having directions ready, getting the luggage, etc.
UPDATE 3/3/10 : A great description of the service from "Disney Daddy" Chuck Lionberger
